Publication date: Jul 08, 2025
The coronavirus pandemic in China ended in 2022, and stringent control measures were lifted in 2023. This study investigated the pathogen and endemic characteristics of enteroviruses (EVs) in patients with influenza-like illness (ILI) in Hangzhou, China, in 2023, providing a foundation for the prevention and control of EV infections. Throughout 2023, 3,480 throat swab samples were collected from hospitals across Hangzhou. Among these, 130 were positive for EVs, with a positivity rate of 3. 74%. Successful sequencing and typing were achieved for 91 cases (70. 00%, 91/130), which included four enterovirus A (EV-A), three enterovirus B (EV-B), and one enterovirus D (EV-D) species. EV-A was predominant in 94. 51% (86/91) of the samples, followed by EV-B (4. 40%, 4/91) and EV-D (1. 10%, 1/91). Notably, coxsackievirus A6 was the dominant genotype detected, accounting for 60. 44% (55/91) of the samples. Coinfection with 12 distinct non-EV respiratory pathogens was also observed in a significant proportion (75. 82%, 69/91) of the samples. Summer and autumn represented peak periods for EV circulation, and children 
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Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | coinfection |
| disease | MESH | influenza |
| disease | IDO | pathogen |
| disease | MESH | infections |
| pathway | REACTOME | Reproduction |
| disease | MESH | Enterovirus Infections |
| disease | MESH | Respiratory Tract Infections |