Breaking the Silence: A Case for Early Intervention in Profound Adolescent Hearing Loss.

Publication date: Jun 01, 2025

Progressive unilateral hearing loss (PUHL) in adolescents is uncommon and presents diagnostic challenges due to its varied etiologies, including infections, ototoxicity, congenital anomalies, and autoimmune conditions, though many cases remain idiopathic. We report a 16-year-old male with a history of COVID-19, dengue at age 14, and recurrent headaches, who developed left-sided hearing loss progressing to profound unilateral deafness. Audiometry confirmed sensorineural hearing loss (SNHL) of 97 dB HL in the left ear and 35 dB HL in the right. Despite multiple evaluations, no definitive etiology was identified. Differential diagnoses included post-viral sequelae, congenital anomalies (e. g., Mondini dysplasia), and nasal obstruction, though insurance limitations restricted further testing. The patient discontinued hearing aid use due to limited benefit and experienced social withdrawal, impacting both academic performance and overall well-being. This case underscores the importance of early recognition and a systematic, multidisciplinary approach to PUHL, including imaging and genetic testing, given its potential impact on social development, mental health, and long-term outcomes.

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Concepts Keywords
Audiometry adolescents
Dysplasia diagnostic limitations
Old post-viral hearing loss
Unilateral social withdrawal
Viral

Semantics

Type Source Name
disease IDO intervention
disease MESH Hearing Loss
disease MESH unilateral hearing loss
disease MESH infections
disease MESH ototoxicity
disease MESH anomalies
disease IDO history
disease MESH COVID-19
disease MESH dengue
disease MESH sensorineural hearing loss
disease MESH etiology
disease MESH sequelae
disease MESH nasal obstruction
pathway REACTOME Reproduction
disease IDO facility
drug DRUGBANK Coenzyme M
disease MESH aids
disease MESH bilateral hearing loss
disease MESH hypertrophy
disease IDO infection
drug DRUGBANK Isoxaflutole
disease MESH complete hearing loss
disease MESH viral infections
disease MESH vertigo
disease MESH tinnitus
disease MESH meningitis
disease MESH enlarged vestibular aqueduct
disease MESH syndrome
disease MESH symptom exacerbation
disease MESH emotional distress
disease MESH depression
disease MESH anxiety
disease MESH stenosis
disease MESH sudden hearing loss
disease MESH arbovirus infection
disease MESH ear infections
disease MESH bacterial meningitis
disease MESH rhinosinusitis

Original Article

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