Publication date: Jul 10, 2025
To investigate whether anterior uveitis developing after BNT162b2 COVID-19 vaccination-classified as Autoimmune/Inflammatory Syndrome Induced by Adjuvants (ASIA)-exhibits distinct clinical features compared to idiopathic uveitis. This single-center retrospective study analyzed records of patients diagnosed with non-infectious anterior uveitis between June 1, 2021, and December 31, 2022. Patients were categorized into two groups: post-vaccine ASIA-related uveitis (Group 1) and idiopathic uveitis (Group 2). A total of 62 patients were included: 12 in Group 1 and 50 in Group 2. The mean age was similar (33. 8 +/- 10. 4 vs. 35. 1 +/- 10. 8 years; p = 0. 547), with male predominance in both groups (61. 1% vs. 58. 5%). Group 1 had significantly milder anterior chamber inflammation (1. 94 +/- 0. 64 vs. 2. 85 +/- 0. 94; p
| Concepts | Keywords |
|---|---|
| December | autoimmunity |
| Infectious | BNT162b2 vaccine |
| June | inflammation |
| Vaccination | uveitis |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | Anterior Uveitis |
| disease | MESH | Syndrome |
| disease | IDO | entity |
| disease | MESH | COVID-19 |
| disease | MESH | uveitis |
| disease | MESH | inflammation |
| disease | MESH | autoimmunity |