Multilayer networks describing urban interactions for building the digital twins of five cities in Spain.

Publication date: Jul 15, 2025

Networks specifying who interacts with whom are crucial for mathematical models of epidemic spreading. In the context of emerging diseases, these networks have the potential to encode multiple interaction contexts where non-pharmaceutical interventions can be introduced, allowing for proper comparisons among different intervention strategies in a plethora of contexts. Consequently, a multilayer network describing interactions in a population and detailing their contexts in different layers constitutes an appropriate tool for such descriptions. These approaches however become challenging in large-scale systems such as cities, particularly in a framework where data protection policies are enhanced. In this work, we present a methodology to build such multilayer networks and make those corresponding to five Spanish cities available. Our work uses approaches informed by multiple available datasets to create realistic digital twins of the citizens and their interactions and provides a playground to explore different pandemic scenario in realistic settings for better preparedness.

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Concepts Keywords
Mathematical Cities
Pandemic COVID-19
Spanish Humans
Twins Pandemics
Urban Spain

Semantics

Type Source Name
disease IDO intervention
drug DRUGBANK Tropicamide
drug DRUGBANK Coenzyme M
disease MESH infectious diseases
disease MESH COVID 19
disease IDO contact tracing
disease MESH privacy
drug DRUGBANK Spinosad
disease MESH pathogen transmission
disease IDO process
disease IDO algorithm
disease MESH educational levels
drug DRUGBANK Isoxaflutole

Original Article

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