Increased Adiposity Impairs Vascular Function in Postmenopausal Women in Hemodialysis.

Publication date: Jul 16, 2025

This study examines the impact of increased body fat on vascular function in postmenopausal women and old men with chronic kidney disease (CKD) undergoing hemodialysis. We included thirty-four postmenopausal CKD-women under hemodialysis (PMW-CKD-HDys) and thirty-one age-matched CKD men also under hemodialysis (M-CKD-HDys). We assessed blood pressure and endothelial function (EFn) through measurements of flow-mediated dilation (FMD). We also evaluated systolic and diastolic blood pressure (SBP and DBP), body mass index (BMI), Fat Total Index (FTI), and Lean Total Index (LTI). A subgroup of CKD-HDys patients infected with COVID 19, were also evaluated on their endothelial function. Our findings indicate that SBP was significantly higher in M-CKD-HDys (149+/-2 mmHg) than in PMW-CKD-HDys (141+/-3 mmHg; p

Concepts Keywords
Fat Chronic Kidney Disease
Hemodialysis Hemodialysis
Kidney Obesity
Women Postmenopausal Women
Vascular Function

Semantics

Type Source Name
disease MESH chronic kidney disease
disease IDO blood
disease MESH COVID 19
disease MESH Obesity

Original Article

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