Publication date: Jul 11, 2025
Recent studies have suggested an increased incidence of various lung diseases following COVID-19 vaccination. However, causal relationships have not been definitively established. We conducted a two-sample Mendelian randomization (MR) study using publicly available genome-wide association study data to investigate potential causal relationships between COVID-19 vaccination status as the exposure and 14 different lung diseases as outcomes. The analytical methods included random-effects inverse-variance weighting, MR Egger, and weighted median, with additional heterogeneity and sensitivity analyses. Seven instrumental variables for exposure were selected (P
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | COVID-19 |
| disease | MESH | lung diseases |
| disease | MESH | respiratory diseases |
Original Article
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