Publication date: Jul 18, 2025
Immunoassays for serology have advanced from radio-immunoassays to multiplexed micro-array-based technologies over the past years. Comparative studies can assist users in selecting an assay platform based on its applicability and performance characteristics. This study compared a 9-plex commercial VaxArray Coronavirus SeroAssay (InDevR) and a 10-plex semi-custom Coronavirus SeroAssay (MSD) with a panel of human serum samples. The MSD assay showed superior dynamic range and sensitivity across all coronavirus serotypes, while both assays met accuracy (100 +/- 20 %) and precision (%CV

| Concepts | Keywords |
|---|---|
| Coronavirus | Meso scale discovery |
| Immunoassay | Microarray ELISA |
| Multiplex | Multiplexed immunoassay |
| Precision | Serology |
| Serotype specific IgG | |
| VaxArray |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | IDO | assay |
| drug | DRUGBANK | Methionine |
Original Article
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