Publication date: Jul 17, 2025
This study aimed to compare the frequency and clinical characteristics of seizures with fever (SWF) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza A. Data of patients below 18 years of age diagnosed with either SARS-CoV-2 or influenza A infections in our hospital were retrospectively analyzed. Approximately 83 (14. 4%) patients of SARS-CoV-2 and 68 (7. 3%) of influenza A cases had seizures. Among 83 patients with SARS-CoV-2 induced seizures, 10 exhibited afebrile seizures and 65 (11. 6%) exhibited SWF, whereas all 69 patients with influenza A-induced seizures exhibited SWF. Among the children with SWF, 23. 1% of those with SARS-CoV-2 and 42. 2% of those with influenza were aged above 5 years. In addition, the frequency of SWF caused by SARS-CoV-2 increased significantly from 2022 onward. Overall, SARS-CoV-2 is associated with a higher frequency of SWF than influenza A, and it can also induce afebrile seizures.
| Concepts | Keywords |
|---|---|
| Coronavirus | afebrile seizure |
| Increased | epilepsy |
| Influenza | influenza A |
| Pediatric | SARS-CoV-2 |
| Seizures | seizure |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | Seizure |
| pathway | KEGG | Influenza A |
| disease | MESH | Infections |
| disease | MESH | influenza |
| disease | MESH | epilepsy |