SARS-CoV-2 subvariant XEC: emerging challenges amidst the global decline of KP.3.1.1.

Publication date: Jul 24, 2025

The ongoing COVID-19 pandemic has seen the emergence of numerous SARS-CoV-2 variants, each posing distinct public health challenges. The XEC variant, a recombinant Omicron subvariant, has rapidly gained prevalence globally, raising critical questions about its potential implications on health systems and public policy. This paper examines the emergence, spread, and unique characteristics of XEC, especially in the context of the global decline of KP. 3.1. 1, another significant Omicron lineage. We discussed the public health implications, including vaccine effectiveness, genomic surveillance, and healthcare system preparedness, underscoring the need for adaptive strategies in response to evolving SARS-CoV-2 variants.

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Concepts Keywords
Global Cov
Healthcare Covid
Pandemic Decline
Recombinant Emergence
Surveillance Emerging
Global
Implications
Kp
Omicron
Ongoing
Public
Sars
Subvariant
Variants
Xec

Semantics

Type Source Name
disease MESH COVID-19 pandemic
pathway REACTOME Reproduction
drug DRUGBANK Nonoxynol-9
disease MESH infectious diseases
disease MESH dengue
drug DRUGBANK Coenzyme M
disease MESH community transmission
disease MESH infection
disease MESH clinical significance
disease IDO host
disease IDO process
disease IDO protein
disease MESH sore throat
disease MESH Influenza
disease IDO contact tracing
disease MESH burnout
drug DRUGBANK Etoperidone
disease MESH emergencies
disease MESH emerging infectious diseases
disease IDO history

Original Article

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