Type II Diabetes Mellitus and COVID-19: Exploring Insulin Management in Patients from Family Medicine Clinics.

Publication date: Jul 04, 2025

The COVID-19 pandemic disrupted routine care for individuals with type 2 diabetes mellitus (T2DM), raising concerns about its impact on glycemic control and medication management. This study evaluated the relationship between insulin use and glycemic control among T2DM patients during the pandemic. A retrospective analysis was conducted using deidentified clinical and prescription data from two family medicine clinics, comparing data from the pre-COVID-19 period (1 March 2019-13 March 2020) and during the COVID-19 pandemic (14 March 2020-31 March 2021). Patients included had at least two A1c values before the COVID and one during the COVID. A1c control was defined as less than 8%. Among 992 patients, 238 experienced a change in A1c status: 128 improved and 110 worsened. Mean A1c remained stable at 8. 2 across both periods. A majority of patients who improved were using insulin during the COVID-19 era, although some discontinued insulin at some point during the study period. These findings suggest that consistent insulin therapy may have helped maintain glycemic control despite healthcare disruptions. This study highlights the importance of sustained medication management and suggests that integrating telehealth and pharmacist-led care could support diabetes control during future healthcare system challenges.

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Concepts Keywords
Basel COVID-19
Diabetes diabetes
Pandemic insulin management
Therapy pandemic

Semantics

Type Source Name
pathway KEGG Type II diabetes mellitus
disease MESH COVID-19
disease MESH type 2 diabetes mellitus
disease MESH Diabetes Mellitus
drug DRUGBANK Cyclic Adenosine Monophosphate
drug DRUGBANK Coenzyme M
disease MESH insulin resistance
pathway KEGG Insulin resistance
disease MESH lifestyles
disease MESH complications
drug DRUGBANK Dextrose unspecified form
disease MESH cardiovascular disease
disease IDO cell
disease MESH hyperglycemia
disease MESH infection
disease MESH psychological distress
disease MESH medication access

Original Article

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