Publication date: Jul 26, 2025
These include sleep disturbances, headaches, fatigue, dizziness, and other symptoms the researchers mapped in their entirety from microbiome changes to metabolites, immune responses, and clinical symptoms. “Despite diverse data collection methods, common disease signatures emerged in fatty acids, immune markers, and metabolites,” Oh said. “New research by The Jackson Laboratory, Duke University, and the Bateman Horne Center reveals that chronic fatigue syndrome (ME/CFS) may leave detectable biological fingerprints in the body. “We integrated clinical symptoms with cutting-edge omics technologies to identify new biomarkers of ME/CFS,” Oh said. “To conduct the study, the researchers analyzed comprehensive data collected from the Bateman Horne Center, a leading ME/CFS, long COVID, and fibromyalgia research center in Salt Lake City, Utah. Dr. “Our goal is to build a detailed map of how the immune system interacts with gut bacteria and the chemicals they produce,” Oh said. “Our data indicate these biological disruptions become more entrenched over time,” Unutmaz said.
| Concepts | Keywords |
|---|---|
| Driving | Bateman |
| Fibromyalgia | Biomarkers |
| Microbiologist | Cfs |
| Utah | Chronic |
| Covid | |
| Fatigue | |
| Gut | |
| Immune | |
| Individuals | |
| Long | |
| Microbiome | |
| Said | |
| Symptoms | |
| Syndrome | |
| Unutmaz |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | chronic fatigue syndrome |
| disease | MESH | long COVID |
| disease | IDO | process |
| pathway | REACTOME | Immune System |
| pathway | REACTOME | Metabolism |
| disease | IDO | blood |
| disease | MESH | syndrome |
| disease | MESH | abnormalities |
| disease | MESH | chronic pain |
| disease | MESH | viral infections |
| disease | MESH | lifestyle |
| disease | MESH | fibromyalgia |
| disease | IDO | cell |
| disease | IDO | symptom |
| drug | DRUGBANK | Pentaerythritol tetranitrate |
| disease | MESH | sleep disorders |
| drug | DRUGBANK | Butyric Acid |
| disease | MESH | inflammation |
| disease | MESH | tryptophan |
| drug | DRUGBANK | L-Tryptophan |
| pathway | REACTOME | Fatty acids |
| disease | IDO | bacteria |