Publication date: Jul 28, 2025
Primary graft dysfunction (PGD) is a form of immediate post-transplant acute lung injury associated with increased risk of mortality, and it is possible that respiratory viruses (RVs) at the time of transplant may augment this. We retrospectively studied all adult lung transplant recipients transplanted in our program from 2017 to 2020, with a primary outcome of grade 3 PGD (PGD3), defined as edema on chest X-ray and arterial oxygen/fraction of inspired oxygen ratio 30 (odds ratio 0. 93 [95% confidence interval 0. 38-2. 49; p = 0. 8845]). Perioperative RVs were not associated with a difference in the risk of PGD3 in our cohort. This may have implications for donor and recipient selection and preoperative evaluation.
| Concepts | Keywords |
|---|---|
| Rvs | lung transplantation |
| Transplant | primary graft dysfunction |
| Viruses | respiratory virus |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | Primary Graft Dysfunction |
| disease | MESH | lung injury |
| disease | MESH | edema |
| drug | DRUGBANK | Oxygen |