Publication date: Aug 01, 2025
This study aims to compare the clinical profiles, outcomes, and mortality-related risk factors of COVID-19-associated mucormycosis (CAM) with cases identified before the pandemic. Additionally, it seeks to evaluate the impact of the COVID-19 pandemic on the epidemiology and severity of mucormycosis infections. Retrospective, observational study. The study was conducted across multiple medical centers in Shiraz, Iran. We reviewed clinical data of patients diagnosed with mucormycosis before and during the COVID-19 pandemic. The study included a detailed analysis of demographic profiles, clinical characteristics, risk factors, treatment outcomes, and mortality. Mortality-related risk factors were specifically analyzed through logistic regression models to identify predictors of poor outcomes in CAM patients. The study included 122 cases of mucormycosis, with 85 cases associated with COVID-19. Patients with CAM showed higher prevalences of diabetes mellitus and hypertension compared to pre-pandemic cases, while malignancies were higher in peri-pandemic cases than in CAM cases (p
| Concepts | Keywords |
|---|---|
| Diabetes | COVID-19 |
| Epidemiology | Diabetes Mellitus |
| Iran | Mortality |
| Models | Mucormycosis |
| Mucormycosis | Risk Factors |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | Mucormycosis |
| disease | MESH | COVID-19 |
| disease | MESH | infections |
| disease | MESH | diabetes mellitus |
| disease | MESH | hypertension |
| disease | MESH | malignancies |