A Multicenter, Open-Label, Randomized Phase 2a Study to Evaluate Safety and Efficacy of Ratutrelvir and Standard of Care in Non-hospitalized Symptomatic Adult Participants With Mild to Moderate COVID-19

A Multicenter, Open-Label, Randomized Phase 2a Study to Evaluate Safety and Efficacy of Ratutrelvir and Standard of Care in Non-hospitalized Symptomatic Adult Participants With Mild to Moderate COVID-19

Publication date: Sep 03, 2025

This is an Early-stage Clinical Trial to Determine a Safe and Effective Dose for Ratutrelvir in Patients With Mild to Moderate COVID-19. It will also learn about the safety of drug Ratutrelvir. Participants will take a study drug as well as a standard therapy. A descriptive statistics will be used to present the study results.

Concepts Keywords
Asthma Covid
Cyp3a4 Efficacy
Hospitalization Evaluate
Nirmatrelvir Label
Statistics Mild
Moderate
Multicenter
Open
Participants
Phase
Prior
Randomized
Ratutrelvir
Safety
Standard

Semantics

Type Source Name
disease MESH COVID-19
pathway REACTOME SARS-CoV-2 Infection
disease IDO history
drug DRUGBANK Oxygen
disease MESH liver disease
pathway REACTOME Immune System
disease MESH respiratory diseases
disease MESH bronchial asthma
disease MESH chronic obstructive pulmonary disease
disease MESH infection

Original Article

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