Publication date: Jun 18, 2025
Bleeding and thromboembolic events (BTE) increase the mortality of COVID-19 acute respiratory distress syndrome (ARDS) treated with extracorporeal membrane oxygenation (ECMO). The current analysis aimed to assess frequency and determinants of BTE according to their location and severity in a retrospective analysis of the German ECMO COVID-19 registry. Logistic regression was applied to identify factors influencing ICU survival as well as variables associated with risks of BTE. In total, 708 of 945 patients (75%) suffered from BTE. Overall, 1,348 events were registered, including 406 (30%) major bleeding and 258 (19%) major thromboembolic events. Most common major bleeding locations were intracranial (n = 133, 10%) and pulmonary bleeding (n = 116, 9%). In-ICU survival was 35, 46% without BTE and 22% with major bleeding (p
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| Concepts | Keywords |
|---|---|
| German | bleeding |
| Pulmonary | COVID-19 |
| Thrombosis | extracorporeal membrance oxygenation |
| thromboembolism |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | bleeding |
| disease | MESH | thrombosis |
| disease | MESH | COVID-19 |
| disease | MESH | acute respiratory distress syndrome |
| disease | MESH | Emergency |
| drug | DRUGBANK | 2′-fluoro-5-ethylarabinosyluracil |
| disease | MESH | Hypertension |
| disease | MESH | Peripheral Vascular Disease |
| disease | MESH | Heart Failure |
| disease | MESH | syndrome |
| disease | MESH | thromboembolism |