Increase in benign acute childhood myositis in the post-COVID era: a retrospective study from a tertiary pediatric center.

Increase in benign acute childhood myositis in the post-COVID era: a retrospective study from a tertiary pediatric center.

Publication date: Sep 05, 2025

Benign Acute Childhood Myositis (BACM) is a transient, self-limiting muscular condition that typically follows viral infections, especially influenza. The COVID-19 pandemic disrupted the circulation of respiratory viruses, altering the epidemiology of related post-infectious complications. This study investigates trends in BACM incidence, clinical features, and viral etiology before and after the pandemic. We conducted a retrospective study of BACM cases diagnosed at a tertiary children’s hospital in Italy between August 2017 and June 2025. Cases were grouped into pre-COVID (2017-2021) and post-COVID (2021-2025) periods. Demographic, clinical, laboratory, and virological data were analyzed. Incidence trends were compared with national ILI surveillance data. A total of 145 BACM cases were identified-28 pre-COVID and 117 post-COVID-corresponding to a 140% increase in incidence (IRR 2. 41, 95% CI: 1. 60-3. 64, p 

Concepts Keywords
Influenza Acute Disease
Italy Adolescent
Pediatric Child
Surveillance Child, Preschool
COVID-19
Female
Hospitals, Pediatric
Humans
Incidence
Infant
Influenza
Influenza, Human
Italy
Male
Myositis
Myositis
Pandemic
Retrospective Studies
SARS-CoV-2
Tertiary Care Centers
Viral

Semantics

Type Source Name
disease MESH myositis
disease MESH viral infections
disease MESH influenza
disease MESH COVID-19 pandemic
disease MESH complications
disease MESH etiology
disease MESH Acute Disease

Original Article

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