Unravelling Health and Frequent Symptoms and Voice Characteristics Evolution Over Time of Users of the Long COVID Companion Application to Develop Voice Biomarkers of Frequent Long Covid-related Symptoms

Unravelling Health and Frequent Symptoms and Voice Characteristics Evolution Over Time of Users of the Long COVID Companion Application to Develop Voice Biomarkers of Frequent Long Covid-related Symptoms

Publication date: Sep 04, 2025

The LIH DDP research team focuses its research topics on vocal biomarkers and Long COVID, among others. Voice is indeed a promising tool to monitor health, as it contains many information on our health and is easy to collect. The development of vocal biomarkers of Long COVID-related symptoms could improve the remote monitoring of the health status of people affected by this disease. The LIH developed the Long COVID Companion (LCC) app in collaboration with the ApresJ20 Long COVID patient association in France to support patients in their daily lives. LCC app users will be invited to participate in this study to collect voice recordings at the same time as health-related data. The objectives of this study are: Primary objective: To develop vocal biomarker candidates for the main Long COVID symptoms (fatigue, brain fog, respiratory problems, sleep issues, stress, anxiety,. .) in a population of people with Long COVID. Secondary objectives: * to assess the intra-individual longitudinal evolution of voice characteristics of people with LC * to assess app usability and acceptability in the long-term.

Concepts Keywords
April Long COVID
Cheap symptoms
Medicine Vocal biomarkers
Pacing
Smartphone

Semantics

Type Source Name
disease MESH Long COVID
drug DRUGBANK Mitometh
disease MESH health status
disease MESH brain fog
disease MESH anxiety
disease MESH COVID-19

Original Article

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