Association of Ventilatory Ratio with Acute Cor Pulmonale and Mortality in COVID-19 ARDS: A Cohort Study.

Association of Ventilatory Ratio with Acute Cor Pulmonale and Mortality in COVID-19 ARDS: A Cohort Study.

Publication date: Sep 08, 2025

PurposeAn elevated ventilatory ratio (VR) and acute cor pulmonale (ACP) are associated with mortality in ARDS patients. The primary aim of this study was to assess the association between VR and ACP in patients with COVID-19-related ARDS (C-ARDS). The secondary objectives were to analyze the association between VR and ICU mortality, describe VR temporal behavior in survivors and non-survivors, and evaluate the association between VR and pulmonary embolism. Materials and MethodsWe studied a cohort of patients with C-ARDS. The VR was calculated using a validated formula. Echocardiography was used to diagnose ACP, and CT pulmonary angiography was performed to identify PE. To evaluate the associations between VR and ACP, mortality, and PE, a generalized logistic regression model was used. ResultsOf the 140 subjects, 60 (43%) had a VR 

Concepts Keywords
Angiography Acute Cor Pulmonale
Covid COVID-19-associated ARDS
Survivors Ventilatory Ratio

Semantics

Type Source Name
disease MESH Acute Respiratory Distress Syndrome
disease MESH pulmonary embolism
disease MESH COVID-19
disease MESH Cor Pulmonale

Original Article

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