Colorectal Cancer Surgical Pathology: Comparative Study in Lebanon Before and After the Economic Collapse.

Colorectal Cancer Surgical Pathology: Comparative Study in Lebanon Before and After the Economic Collapse.

Publication date: Sep 01, 2025

Colorectal cancer (CRC) screening and early detection reduce mortality. Curative treatment is based on surgical resection, and pathological analysis plays a key role in management. In Lebanon, the impact of the COVID-19 pandemic on healthcare has been compounded by an unprecedented socio-economic crisis in 2020. This has deteriorated access to medical care and could have delayed CRC diagnosis and treatment. The study evaluates the impact of the economic collapse on CRC in Lebanon by comparing characteristics of patients operated on in 2020 and 2021 (post-crisis period) to those operated on in 2018 and 2019 (pre-crisis period). This retrospective study included patients who underwent surgical resection for colorectal adenocarcinoma at a tertiary care center in Lebanon between 01/01/2018 and 12/31/2021. Patients were divided into two groups according to the corresponding period, and the demographic, clinical, and pathological characteristics were compared. Among the 169 patients included, 89 (53%) were operated on in the pre-crisis period and 80 (47%) in the post-crisis period. We reported that in the post-crisis period: more patients presented with clinical complications requiring urgent admission (30% vs. 16%), more tumors were classified as T4b (10% vs. 2%), and more tumors presented lymphatic emboli (65% vs. 45%), perineural (51% vs. 22%) and perivascular invasion (40% vs. 19%) (p 

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Concepts Keywords
Adenocarcinoma Adenocarcinoma
Economic Aged
Hoboken colorectal cancer
Colorectal Neoplasms
COVID-19
economic crisis
Economic Recession
Female
Humans
Lebanon
Lebanon
Male
Middle Aged
oncologic pathology
public health
Retrospective Studies
SARS-CoV-2
surgical pathology

Semantics

Type Source Name
disease MESH Colorectal Cancer
pathway KEGG Colorectal cancer
disease IDO role
disease MESH COVID-19 pandemic
disease MESH adenocarcinoma
disease MESH complications
disease MESH tumors
drug DRUGBANK Coenzyme M

Original Article

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