Publication date: Sep 12, 2025
Candidozyma auris (formerly Candida auris) has emerged as a significant multidrug-resistant pathogen. Among 140 antifungal-resistant Candida spp. isolates, 120 were identified as C. auris using chromogenic agar, VITEK 2, and MALDI-TOF. Most cases (60%) were males, and 59% were aged ≥ 60 years. Bloodstream infections were predominant (60. 8%), followed by respiratory (20. 8%), urinary tract (15%), and other sites. Liver transplantation (35. 8%) was the most common underlying risk factor, followed by post-COVID-19 (30. 8%) and cancer (25%). All isolates exhibited thermotolerance, halotolerance, anaerobic blood hemolysis, and biofilm formation. Significant association was observed between virulence enzymes activity and both specimen source and clinical conditions (P
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| Concepts | Keywords |
|---|---|
| Aged60 | Biofilm |
| Biofilm | Candida auris |
| Candidozyma | Epidemiology |
| Hemolysis | Hemolysis |
| Virulence | Multidrug resistance |
| Virulence |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | IDO | pathogen |
| disease | MESH | Bloodstream infections |
| disease | MESH | COVID-19 |
| disease | MESH | cancer |
| disease | IDO | blood |
| disease | MESH | hemolysis |
| pathway | KEGG | Biofilm formation |
| disease | IDO | virulence |