Publication date: Sep 16, 2025
Acute respiratory infections (ARI) exhibit varying lethality rates, influenced by individual and population factors. This retrospective study aimed to analyse infection frequency, clinical characteristics, and factors associated with lethality in hospitalized patients with seasonal ARI pathogens. Virological and demographic data of hospitalized patients ≥ 18 years who tested positive for at least one ARI viral pathogen (Influenza, Adenovirus, Coronavirus, human Metapneumovirus (hMPV), Parainfluenza, Rhinovirus, Respiratory Syncytial Virus (RSV) and SARS-CoV-2) were collected from 07/2022 to 04/2023 at a German tertiary care hospital. Logistic regression analysis was used to analyse factors influencing lethality. Univariate comparisons examined pathogen-specific differences in length of stay and lethality. Among 1,657 hospitalized patients with at least one detected ARI pathogen, 89 (5. 5%) passed away. Logistic regression analysis indicated a significant association between advanced age and lethality (OR = 1. 05 per year, p
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Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | respiratory infections |
| disease | MESH | infection |
| disease | IDO | pathogen |
| disease | MESH | Influenza |
| disease | MESH | Parainfluenza |
| pathway | REACTOME | Reproduction |
| disease | MESH | Infectious Diseases |