Publication date: Sep 17, 2025
Background: Surgical site infections (SSIs) are common after cesarean deliveries, with few studies exploring their correlation with seasonal changes and the coronavirus disease 2019 (COVID-19) pandemic. This study aims to explore the impact of the COVID-19 pandemic and seasonal factors on the rate of SSIs following cesarean delivery. Patients and Methods: A retrospective cohort analysis was conducted to investigate trends in SSI rates following cesarean sections at the International Peace Maternity and Child Health Hospital from January 2017 to September 2024. The study included women who underwent cesarean sections with at least 30 days of post-operative follow-up and met the US Centers for Disease Control and Prevention’s SSI diagnostic criteria. Cases were categorized into pre-pandemic (n = 109), pandemic (n = 87), and post-pandemic normalization groups (n = 88). Statistical analyses included descriptive statistics, t-tests, analysis of variance, and chi-squared tests using SPSS 25. 0, whereas time series analysis used a Seasonal Autoregressive Integrated Moving Average model in Python 3. 12, with significance set at p

| Concepts | Keywords |
|---|---|
| Coronavirus | cesarean section |
| Python | COVID-19 |
| Spring | post-pandemic period |
| Surgical | seasonal variation |
| surgical site infection |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | Coronavirus Disease 2019 |
| disease | MESH | Surgical Site Infection |
| drug | DRUGBANK | Methionine |