Exceptional high number of IPD cases in winter season 2024-2025 in Belgium in concomitance with rise in vaccine serotypes.

Exceptional high number of IPD cases in winter season 2024-2025 in Belgium in concomitance with rise in vaccine serotypes.

Publication date: Sep 17, 2025

Following lifting of containment measures post-COVID, the number of invasive pneumococcal disease (IPD) infections continued to increase, reaching a record number last winter season 2024-2025 in Belgium. This exceptional increase is largely due to high numbers in (older) adults, and mainly an increase of vaccine serotype IPD. Over 95 % of IPD cases last winter could theoretically be prevented by vaccination. Cases of serotypes 12F, 14 and 4 were three or more times higher compared to pre-COVID winter season 2019-2020.

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Concepts Keywords
Belgium Belgium
Invasive Increase
Vaccination IPD
Winter S. pneumoniae
Vaccine serotype

Semantics

Type Source Name
disease MESH pneumococcal disease
disease MESH infections
disease MESH COVID 19
disease IDO country
drug DRUGBANK Pentaerythritol tetranitrate
disease IDO blood
disease IDO susceptibility
disease IDO role
drug DRUGBANK Cysteamine
disease MESH viral infections
disease MESH respiratory infections
disease IDO infection
disease MESH bacterial diseases

Original Article

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