Publication date: Sep 23, 2025
This study aimed to assess the impact of COVID-19 on the prevalence of respiratory pathogens among hospitalized patients with respiratory tract infections in Shanghai, China. Patients with acute respiratory infections (ARIs) hospitalized at Putuo Hospital, Shanghai University of Traditional Chinese Medicine from January 2017 to December 2022 were collected. Indirect immunofluorescence assay (IFA) was used to detect the IgM antibody of nine common pathogens, including Chlamydia pneumoniae (CP), Mycoplasma pneumoniae (MP), parainfluenza virus (PIV), respiratory syncytial virus (RSV), influenza virus A (FluA), influenza virus B (FluB), adenovirus (ADV), Legionella pneumophila (Lp), and Coxiella burnetii (Cb). A total of 24,933 eligible patients were enrolled. The overall detection rate of respiratory pathogens in the pre-outbreak group (2017-2019, 32. 05%) was significantly higher than that in the outbreak group (2020-2022, 11. 48%, P
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| Concepts | Keywords |
|---|---|
| China | acute respiratory infections |
| Covid | COVID-19 |
| Immunofluorescence | hospitalization |
| Pneumoniae | respiratory pathogens |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | IDO | pathogen |
| disease | MESH | infections |
| disease | MESH | COVID-19 pandemic |
| disease | MESH | respiratory tract infections |
| disease | IDO | assay |
| disease | MESH | parainfluenza |
| disease | MESH | influenza |
| disease | IDO | infection |
| drug | DRUGBANK | Tropicamide |