Time series anomaly detection in helpline call trends for early detection of COVID-19 spread across Sweden, 2020.

Time series anomaly detection in helpline call trends for early detection of COVID-19 spread across Sweden, 2020.

Publication date: Sep 24, 2025

Timely detection and surveillance of disease community spread is a potent tool for implementing effective public health interventions. This study investigates the National Telehealth Service (1177 helpline) across 18 regions in Sweden in 2020 to identify early signals of community transmission of COVID-19 at the beginning of the pandemic. Focusing on calls related to key COVID-19 symptoms (cough, fever, and breathing difficulties in adults), we analyze their frequency and distribution across referral categories, comparing them to 2019 data. We employ an explainable time series anomaly detection algorithm using daily call data to identify the first collective anomalies across regions. The results show that anomalies in call data were correlated with, but preceded, the first confirmed case infected in Sweden by a median of 7 days (IQR: 2. 5-10. 5) and the first hospitalized case infected in Sweden by a median of 13 days (IQR: 7. 25-16). They also preceded the estimated onset of community spread, indicated by the absolute confirmed cases (median: 24. 5, IQR: 18. 25-32. 5), and severe outcomes defined by hospitalizations (median: 33, IQR: 27. 25-44). These findings showcase how helpline call monitoring, using time series anomaly detection, can aid early outbreak detection.

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Concepts Keywords
Daily Adult
Fever Algorithms
Hospitalizations Anomaly detection
Surveillance Community spread 
Sweden COVID-19
COVID-19 
Early detection
Early Diagnosis
Helpline calls
Hotlines
Humans
Pandemics
SARS-CoV-2
Sweden
Symptoms
Telemedicine

Semantics

Type Source Name
disease MESH COVID-19
disease MESH community spread
disease IDO algorithm
disease MESH anomalies
disease MESH infections
disease IDO symptom
disease MESH sore throat
disease MESH joint pain
disease IDO infection
drug DRUGBANK Coenzyme M
disease MESH cryptosporidiosis
drug DRUGBANK Water
disease MESH tick borne encephalitis
disease MESH influenza
disease MESH death
disease MESH death Cause
disease IDO country
disease MESH Emergency
drug DRUGBANK Isoxaflutole
drug DRUGBANK Aspartame
drug DRUGBANK Saquinavir
disease IDO process
drug DRUGBANK Methylergometrine
disease MESH Tick Borne Diseases
disease MESH gastroenteritis
disease MESH infectious diseases
pathway REACTOME Reproduction

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