Publication date: Jan 01, 2026
This study investigated the association between preoperative anemia and total knee arthroplasty (TKA) revision risk at a 3-year follow-up. We conducted a multi-institutional retrospective cohort study of patients aged ≥b50 years who underwent primary TKA between 2010 and 2019 using a federated health research network database. Patients were categorized as anemic (hemoglobin eight to 12 g/dL) or nonanemic (≥ 12 g/dL), regardless of sex, and matched 1:1 using propensity scores. The primary outcome was TKA revision within 3 years; the secondary outcomes included periprosthetic joint infection (PJI), mortality, pneumonia, venous thromboembolism, and emergency department visit. After matching (n = 6,477 per group), anemic patients had significantly higher risks of TKA revision (hazard ratio [HR]: 1. 65, P
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | Anemia |
| disease | MESH | included |
| disease | MESH | infection |
| disease | MESH | PJI |
| disease | MESH | pneumonia |
| disease | MESH | venous thromboembolism |
| disease | MESH | emergency |
| disease | MESH | COVID-19 pandemic |
| disease | MESH | Postoperative Complications |