Publication date: Dec 10, 2025
The zero-COVID policy and non-pharmaceutical interventions (NPIs) implemented in response to COVID-19 concurrently influenced the transmission of other respiratory pathogens. In the post-pandemic era following the policy’s cessation, whether the epidemiological patterns of these respiratory pathogens have reverted to pre-pandemic baselines or persisted unchanged remains a subject of interest. The retrospective study analyzed 8,774 cases with acute respiratory tract infections (ARTIs) from 2022 to 2024, with data sourced from 26 children’s hospitals or general hospitals in Hunan Province, to investigate the potential impacts of policy changes on epidemiology. Nine common respiratory pathogens were detected using targeted next-generation sequencing (tNGS) technology. Among children seeking medical care, the overall pathogen positive rate increased (P
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| Concepts | Keywords |
|---|---|
| China | Children |
| Covid | Hunan |
| Epidemiology | Respiratory infection |
| Increased | Virus |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | COVID-19 |
| disease | MESH | respiratory tract infections |
| disease | MESH | Infectious Diseases |
| disease | MESH | Dis |
| drug | DRUGBANK | Guanosine |
| drug | DRUGBANK | Troleandomycin |
| pathway | REACTOME | Reproduction |
| disease | MESH | included |
| drug | DRUGBANK | Coenzyme M |