Publication date: Dec 11, 2025
Pregnant women are at higher risk of severe coronavirus disease 2019 (COVID-19) compared with nonpregnant women of reproductive age. During 2023-2024, the Centers for Disease Control and Prevention recommended COVID-19 vaccination for everyone aged 6 months or older, including pregnant women. Using a test-negative design, we assessed the effectiveness of 2023-2024 COVID-19 vaccines against COVID-19-associated emergency department (ED) and urgent care setting encounters among pregnant women aged 18-45 years presenting for care with COVID-19 symptoms from September 2023 to August 2024. Vaccine effectiveness against COVID-19-associated ED and urgent care encounters of one 2023-2024 COVID-19 vaccine dose was 58% (95% CI, 24-77%) among pregnant women and 37% (95% CI, 29-44%) among nonpregnant women of the same age. The 2023-2024 COVID-19 vaccines were associated with a decrease in COVID-19-associated ED and urgent care encounters among pregnant women and nonpregnant women of reproductive age.
| Concepts | Keywords |
|---|---|
| Coronavirus | Age |
| Pregnant | Aged |
| Vaccination | Associated |
| Care | |
| Coronavirus | |
| Covid | |
| Effectiveness | |
| Encounters | |
| Nonpregnant | |
| Pregnant | |
| Reproductive | |
| Urgent | |
| Vaccine | |
| Vaccines | |
| Women |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | Coronavirus Disease 2019 |
| disease | MESH | emergency |
| disease | MESH | Long Covid |