A countrywide study on post-COVID-19 condition in Brazil: the Epicovid 2.0.

A countrywide study on post-COVID-19 condition in Brazil: the Epicovid 2.0.

Publication date: Jan 01, 2026

The COVID-19 pandemic had severe impacts worldwide. We assessed the occurrence of a post-COVID-19 condition (PCC) in Brazil and described the persistence of symptoms 4 years after the start of the pandemic. A population-based survey was carried out in 133 large cities in 2024. The current prevalence of 21 COVID-19-related symptoms was recorded for all respondents, regardless of infection history. The World Health Organization’s definition of PCC was adopted. Results were described by country region and socio-demographic characteristics. Of the 33 250 individuals sampled, 28. 6% [95% confidence interval (CI) 27. 3 to 30. 0] reported having had COVID-19, of whom 65. 1% (95% CI 62. 7 to 67. 4) fulfilled the criteria for PCC at any time in the past. Prevalence of PCC was highest among those who were hospitalized and needed intubation or oxygen support [85. 3% (95% CI 79. 6 to 89. 7)]. The average number of current symptoms among those with PCC was 7. 21 (95% CI 6. 73 to 7. 69) compared with 2. 77 (95% CI 2. 62 to 2. 92) among those without a COVID-19 history. The most common symptoms for those with COVID-19 history were memory loss, anosmia, loss of sensitivity in the hands, difficulty in concentration, and hair loss. Women and Indigenous individuals presented a higher average number of symptoms compared with those without a history. A high proportion of individuals who suffered from COVID-19 presented symptoms 4 years after the SARS-CoV-2 emergence; almost two-thirds presented PCC. Population-based studies in different countries are necessary to better understand the epidemiology of this serious condition.

Concepts Keywords
Brazil Adolescent
Countrywide Adult
Epidemiology Aged
Women Brazil
Brazil
Child
COVID-19
Female
Humans
Male
Middle Aged
post-COVID-19 condition
Prevalence
SARS-CoV-2
SARS-COV-2
survey
Young Adult

Semantics

Type Source Name
disease MESH COVID-19
drug DRUGBANK Factor IX Complex (Human)
disease MESH PCC
disease MESH infection
drug DRUGBANK Oxygen
disease MESH memory loss
disease MESH anosmia
disease MESH hair loss
drug DRUGBANK Tropicamide
disease MESH Long Covid

Original Article

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