Publication date: Dec 17, 2025
An association between COVID-19 and obstructive sleep apnea (OSA) has been reported in literature. We aimed to address the occurrence and phenotypes of OSA in adults with a history of COVID-19 infection and its possible association with long-COVID. In this matched case-control study, 152 individuals with a history of COVID-19 and 152 without were evaluated in a sleep laboratory. Groups were matched for age, sex, and body mass index. OSA was defined as an apnea-hypopnea index (AHI) ≥15/h. Rapid Eye Movement (REM)-predominant OSA was defined as AHI ≥15/h and REM-AHI/non-REM-AHI ≥2. Fatigue, reported as “frequent/very frequent,” was used as a surrogate marker of long-COVID. The prevalence of OSA was significantly lower in the case group (50. 0 %) compared to the control group (77. 6 %) (p
| Concepts | Keywords |
|---|---|
| Covid | COVID-19 |
| Laboratory | Obstructive sleep apnea |
| Rapid | REM predominant OSA |
| Sleep |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | obstructive sleep apnea |
| disease | MESH | COVID-19 |
| disease | MESH | infection |
| disease | MESH | apnea |
| disease | MESH | Fatigue |
| disease | MESH | Long Covid |