The impact of the COVID-19 pandemic on osteoporotic fractures: a systematic review and meta-analysis.

The impact of the COVID-19 pandemic on osteoporotic fractures: a systematic review and meta-analysis.

Publication date: Dec 01, 2026

Recent reports suggest that the COVID-19 pandemic and associated lockdowns may have influenced the epidemiology of osteoporotic fractures, but results vary across regions and fracture types. The aim of this study was to provide evidence-based insights into the impact of the pandemic on osteoporotic fracture incidence. We searched four databases (PubMed, Embase, Cochrane Library, and Web of Science) up to August 2025 for observational or retrospective studies comparing osteoporotic fracture incidence during the COVID-19 pandemic (2020) with the pre-pandemic period (2019). The primary outcome of interest was the change in fracture incidence, analysed using risk ratios (RR) with 95% confidence intervals (CI) in Review Manager 5. 4. Subgroup analyses were performed by sex, geographic region, and fracture type. Nine studies meeting the inclusion criteria were analysed. Overall, “all types” of osteoporotic fractures showed a significant decrease during the pandemic (RR = 0. 85, 95% CI 0. 80-0. 91, p 

Concepts Keywords
Epidemiology COVID-19
Library COVID-19
Manager Female
Sex fracture
Hip Fractures
Humans
Incidence
Male
meta-analysis
osteoporosis
Osteoporotic Fractures
Pandemics
SARS-CoV-2
SARS-CoV-2
Spinal Fractures

Semantics

Type Source Name
disease MESH COVID-19 pandemic
disease MESH osteoporotic fractures
disease MESH Hip Fractures
disease MESH osteoporosis
disease MESH Spinal Fractures

Original Article

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