Publication date: Jul 01, 2026
Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, affects multiple systems, including the oral cavity, with ulcers, taste changes, and mucosal lesions. Existing studies are limited in scope, highlighting the need for large-scale studies to clarify the prevalence and clinical relevance of these oral outcomes. We conducted a retrospective cohort study using the TriNetX Research Network to analyze COVID-19 patients from 2020 to 2025. Queried oral conditions, including ulcers, taste alterations, salivary disturbances, and mucosal lesions. Propensity score matching was used to balance age, sex, and comorbidities. Odds ratios (ORs) with 95% confidence intervals (CIs) were calculated, with significance set at P
| Concepts | Keywords |
|---|---|
| Coronavirus | Adult |
| Taste | Aged |
| Ulcers | COVID-19 |
| Female | |
| Humans | |
| Male | |
| Middle Aged | |
| Mouth Diseases | |
| Prevalence | |
| Retrospective Studies | |
| Risk Factors | |
| Taste Disorders |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | COVID-19 |
| disease | MESH | ulcers |
| drug | DRUGBANK | Isoxaflutole |
| disease | MESH | aphthous ulcers |
| disease | MESH | stomatitis |
| disease | MESH | Long Covid |
| disease | MESH | Mouth Diseases |
| disease | MESH | Taste Disorders |