Publication date: May 19, 2026
During the COVID pandemic increased rates of intensive care unit (ICU) admission, mechanical ventilation, caesarean delivery, and preterm birth among women with SARS-CoV-2 infection in pregnancy were recorded. This study describes the clinical course and perinatal outcomes of pregnant women with COVID-19 across pre- and post-vaccination periods. This study included all pregnant women with confirmed SARS-CoV-2 infection who subsequently delivered at the University General Hospital of Larissa between March 2020 and May 2023. Demographics, comorbidities, gestational age at infection and at delivery, COVID-19 symptoms, need for hospitalization, obstetric complications, mode of delivery, and neonatal outcomes were documented. An assessment of ischemia-modified albumin (IMA) was performed in a subset of women. A total of 327 women (including 14 twin gestations) were recorded. Most women experienced mild disease while a minority required hospital admission, or intensive care (1. 8 and 0. 3% for the studied population, respectively). Fever and upper respiratory symptoms predominated, while radiologic evidence of pneumonia was rare. Overall preterm birth (
| Concepts | Keywords |
|---|---|
| Caesarean | clinical outcomes |
| Greece | COVID-19 |
| Hospitalization | ischemia-modified albumin |
| Pneumonia | perinatal outcomes |
| Pregnancy | pregnancy |
| vaccination |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | Clinical Course |
| disease | MESH | COVID-19 |
| disease | MESH | preterm birth |
| pathway | REACTOME | SARS-CoV-2 Infection |
| disease | MESH | included |
| disease | MESH | infection |
| disease | MESH | Fever |
| disease | MESH | pneumonia |