A 19-layer convolutional neural network for accurate COVID-19 detection in chest X-ray images: comparative analysis with pretrained networks.

A 19-layer convolutional neural network for accurate COVID-19 detection in chest X-ray images: comparative analysis with pretrained networks.

Publication date: Jun 02, 2026

One of the most conspicuous developments in the unprecedented worldwide epidemic of COVID-19 is the pressing demand for reliable diagnostic tools. Utilizing artificial intelligence (AI) and image processing algorithms, this work proposes a novel 19-layer Convolutional Neural Network (CNN) for accurate COVID-19 detection from chest X-ray images. This CNN architecture supports structure with single/multiple labels for three classes (i. e., for classification between layers like viral pneumonia, normal, and COVID-19) and four classes (i. e., lung opacity, normal, COVID-19, and pneumonia). Across the accuracy, specificity, precision, sensitivity, confusion matrix, F1-score, and other metrics, our model was compared to periutils net from the literature such as popular pre-trained networks(Inception, AlexNet, ResNet50, SqueezeNet, VGG19). Experimental results show that the proposed CNN outperforms existing methods, providing an effective diagnostic tool with the potential for clinical usage. This means AI algorithms as advanced as Cogito could start making decisions about COVID-19 and inform clinicians about how to handle the case.

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Concepts Keywords
COVID-19
Early diagnosis
Radiology images
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Semantics

Type Source Name
disease MESH COVID-19
disease MESH image
disease MESH viral pneumonia
disease MESH pneumonia
disease MESH confusion
pathway REACTOME Reproduction
disease MESH included
drug DRUGBANK Coenzyme M
disease MESH common cold
disease MESH coronavirus infections
disease MESH infections
disease MESH bacterial pneumonia
disease MESH Tuberculosis
pathway KEGG Tuberculosis
drug DRUGBANK Aspartame
drug DRUGBANK Flunarizine
drug DRUGBANK L-Valine
disease MESH Residual block
drug DRUGBANK Isoxaflutole
drug DRUGBANK Saquinavir
disease MESH heart failure
disease MESH superinfections
disease MESH death
disease MESH acute lung injury
disease MESH pulmonary embolism
disease MESH brain tumor
disease MESH lung cancer
disease MESH metastasis
drug DRUGBANK Snail unspecified
disease MESH Tumor
drug DRUGBANK (S)-Des-Me-Ampa
drug DRUGBANK Elm
disease MESH kidney stone
disease MESH myocardial infarction

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