Worldwide prevalence of diabetic ketoacidosis at diagnosis of type 1 diabetes: A systematic review and meta-analysis.

Publication date: Jun 16, 2026

Diabetic ketoacidosis (DKA) is a life-threatening complication of type 1 diabetes (T1D) and a marker of delayed diagnosis, associated with significant morbidity, mortality, and healthcare costs. Global estimates of DKA at T1D onset remain inconsistent. We conducted a systematic review and meta-analysis, searching PubMed (1996), Web of Science (1966), Embase (1947), and Scopus (1980), each from its inception to October 2025, without restrictions. Studies reporting DKA prevalence at diagnosis in individuals

Concepts Keywords
Diabetes Diabetic ketoacidosis
Global Meta-analysis
Healthcare Pediatric endocrinology
Morbidity Systematic review
Type 1 diabetes

Semantics

Type Source Name
disease MESH diabetic ketoacidosis
disease MESH type 1 diabetes

Original Article

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