Publication date: Jun 14, 2026
Loneliness in cancer survivors is associated with a variety of negative consequences to physical and mental health. Research regarding the impact of loneliness on health-related quality of life and mental health outcomes in prostate cancer (PC) survivors is scarce. The current study aimed to investigate prevalence and determinants of loneliness in long-term PC survivors following radical prostatectomy (RP). A total of 3127 PC survivors (mean age 79. 5 years, SD 6. 4) from the multicenter German Familial PC Database returned the study questionnaires during the COVID-19 pandemic, after an average of 17. 4 years (SD = 3. 8) following RP. Loneliness was assessed using a single item measure. Validated self-reporting questionnaires were used to assess anxiety and depressive symptoms, health related quality of life, and frailty. Descriptive statistics, chi-square tests, and logistic regression analysis were conducted to examine the prevalence, correlates, and determinants of loneliness in PC patients. Overall, 16. 6% of patients reported at least some degree of loneliness. Partnership status, depression, and anxiety were significantly associated with loneliness. Individuals living in a partnership experienced lower levels of loneliness (p
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Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | prostate cancer |
| pathway | KEGG | Prostate cancer |
| disease | MESH | cancer |
| disease | MESH | COVID-19 pandemic |
| disease | MESH | anxiety |
| disease | MESH | frailty |