Publication date: Jun 18, 2026
Tuberculosis (TB) remains a major public health challenge in Nigeria, while the overlap between TB and coronavirus disease 2019 (COVID-19) in symptomatic patients has been less clearly described in routine clinical settings. This study assessed the prevalence and determinants of TB and COVID-19 among presumptive TB patients in a tertiary hospital in Port Harcourt, Nigeria. This hospital-based cross-sectional study, conducted between April and August 2024, involved 242 presumptive TB patients attending Rivers State University Teaching Hospital, Port Harcourt recruited using consecutive sampling. Sociodemographic characteristics, medical-related, and behavioural/environmental data were collected using a structured interviewer-administered questionnaire, while TB and COVID-19 were assessed using Xpert Mycobacterium tuberculosis/rifampicin (Xpert MTB/RIF) assay and STANDARD Q COVID-19 Ag Test, respectively. Statistical analysis involved descriptive statistics, chi-square tests, and multivariable logistic regression analyses using GraphPad Prism 9, with statistical significance set at p ≤ 0. 05. TB was detected in 21. 9% of participants; however, no participant tested positive for COVID-19, yielding a COVID-19 prevalence of 0. 0%, and no case of TB/COVID-19 co-infection was identified. None of the sociodemographic characteristics examined was significantly associated with TB prevalence (p > 0. 05). However, contact with someone with prolonged coughing (aOR: 5. 41, 95% CI: 2. 55-11. 70; p
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| Concepts | Keywords |
|---|---|
| Coughing | COVID-19 |
| Interviewer | HIV |
| Mycobacterium | Overcrowding |
| Nigeria | Presumptive tuberculosis patients |
| Smoking | |
| TB/COVID-19 co-infection | |
| Tuberculosis | |
| Ventilation |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | tuberculosis |
| pathway | KEGG | Tuberculosis |
| disease | MESH | COVID-19 |
| drug | DRUGBANK | Rifampicin |
| disease | MESH | co-infection |
| disease | MESH | Long Covid |
| disease | MESH | Infectious Diseases |
| disease | MESH | Dis |
| pathway | REACTOME | Reproduction |
| disease | MESH | included |
| disease | MESH | MLS |
| drug | DRUGBANK | Methylphenidate |
| disease | MESH | infection |
| disease | MESH | death |
| drug | DRUGBANK | Medical air |
| disease | MESH | HIV infection |
| pathway | REACTOME | HIV Infection |
| disease | MESH | chronic cough |
| disease | MESH | cough |
| disease | MESH | fever |
| disease | MESH | weight loss |
| disease | MESH | Severe Acute Respiratory Syndrome |
| drug | DRUGBANK | BCG vaccine |
| disease | MESH | AIDS |
| disease | MESH | diabetes mellitus |
| drug | DRUGBANK | Ethanol |
| drug | DRUGBANK | Saquinavir |