Mental health outcomes and physical activity during the COVID-19 pandemic: A systematic review and meta-analysis of observational studies.

Publication date: Jun 23, 2026

The COVID-19 pandemic disrupted physical activity behaviors and worsened mental health worldwide. This study synthesized observational evidence on relationships between physical activity and depression, anxiety, and stress in adults during COVID-19. A systematic review and multilevel random-effects meta-analysis (PROSPERO CRD42023491651) of observational studies published January 2020-May 2023 included 38 studies with 140,915 adults using validated measures. Physical activity showed significant inverse associations with depression (r = -0. 18; p 

Concepts Keywords
Crd42023491651 anxiety
January COVID-19
Pandemic depression
Therapy exercise

Semantics

Type Source Name
disease MESH COVID-19 pandemic
disease MESH anxiety
disease MESH included

Original Article

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