The stand-alone Ayurveda treatment for the management of COVID-associated mucormycosis (CAM): a case report.

Publication date: Apr 06, 2026

Mucormycosis is a rapidly progressive opportunistic fungal infection predominantly affecting individuals with diabetes or immune compromise. To our knowledge, this report presents one of the first clinically documented cases of invasive Mucormycosis managed exclusively with an Ayurveda-based approach. A 60-year-old male with recent COVID-19 infection (CT severity score 7/25) presented with facial heaviness, lacrimation, and peripheral vision loss. Diagnostic evaluation confirmed invasive mucormycosis through potassium hydroxide testing, histopathology demonstrating vasculoinvasion, fungal culture identifying Mucor species, and radiological findings. Surgical intervention including eye enucleation was advised. Following informed decision-making, the patient opted for stand-alone Ayurvedic management. A structured therapeutic regimen was administered over 15 days and continued for 90 days. The patient demonstrated progressive symptomatic improvement with no reported adverse events. At the three-year follow-up, there was no evidence of clinical recurrence. Laboratory parameters, including liver and renal function, remained within normal limits. Follow-up imaging indicated resolution with residual structural changes. This case documents a rare and complex clinical scenario managed with an Ayurveda-based approach, demonstrating sustained clinical and radiological improvement. While the findings do not permit generalisation, they highlight a state of clinical equipoise and underscore the need for rigorously designed studies to systematically evaluate the safety, effectiveness, and potential role of Ayurveda-based interventions in the management of invasive mucormycosis.

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Concepts Keywords
90days Ayurveda
Ct case report
Diabetes emergency care
Invasive invasive fungai infection
Mucormycosis mucormycosis

Semantics

Type Source Name
disease MESH mucormycosis
disease MESH CAM
disease MESH COVID-19
disease MESH infection
drug DRUGBANK Potassium hydroxide
disease MESH recurrence
drug DRUGBANK Coenzyme M
pathway REACTOME Reproduction
drug DRUGBANK Hydroxide ion
disease MESH emergency
disease MESH fungal infection
disease MESH malignancies
disease MESH necrosis
disease MESH diabetes mellitus
drug DRUGBANK Trestolone
disease MESH double vision
disease MESH hypertension
disease MESH granuloma
disease MESH rhinosinusitis
disease MESH orbital cellulitis
disease MESH aspergillosis
disease MESH inflammation
disease MESH face
disease MESH included
drug DRUGBANK Medical air
drug DRUGBANK Isoxaflutole
disease MESH image
drug DRUGBANK Sodium borate
disease MESH sinusitis
disease MESH sclerosis
disease MESH facial pain
disease MESH nasal blockage
disease MESH diminished vision
drug DRUGBANK Amphotericin B
disease MESH Poisoning
drug DRUGBANK Rasagiline
disease MESH Eye disorders
disease MESH star
drug DRUGBANK Chlorotrianisene
disease MESH death
disease MESH Dis
disease MESH hematologic malignancy
disease MESH zygomycosis
disease MESH coinfection
disease MESH Heavy metal Poisoning
drug DRUGBANK Silver
disease MESH metastasis
disease MESH Lam
drug DRUGBANK Isavuconazole

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