Effect of a Personalized Mobile App on Glucose Control in Adults With Prediabetes and Type 2 Diabetes: Exploratory Pilot Randomized Controlled Trial.

Publication date: Jun 24, 2026

The incidence of type 2 diabetes (T2D) continues to increase, and the lack of individualized therapy strategies hinders patient engagement with and commitment to a healthy lifestyle. The PROTEIN project aimed to facilitate users in choosing healthy living, thereby improving their metabolism and T2D management. This study aims to assess the efficacy of a personalized mobile app to achieve a 5% time in range (TIR) improvement over a 12-week intervention in adults with prediabetes or T2D. We conducted an exploratory pilot randomized controlled trial with 21 individuals with T2D or prediabetes who used a continuous glucose monitoring system and the PROTEIN mobile app for personalized meals and exercise recommendations based on their glucose levels and physical activity. The TIR of the participants increased (P

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Concepts Keywords
Diabetes Adult
Meals Aged
Pilot Blood Glucose
Therapy Blood Glucose
Week CGM
Continuous Glucose Monitoring
continuous glucose monitoring
Diabetes Mellitus, Type 2
Digital Health
Female
glucose management
Glycated Hemoglobin
Glycated Hemoglobin
Glycemic Control
Humans
Male
Middle Aged
Mobile Applications
personalized nutrition
Pilot Projects
Prediabetic State
time in range
type 2 diabetes

Semantics

Type Source Name
drug DRUGBANK Dextrose unspecified form
disease MESH Prediabetes
disease MESH Type 2 Diabetes
pathway REACTOME Metabolism

Original Article

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