Publication date: Jun 18, 2026
Objectives: To investigate the clinical and epidemiological characteristics of respiratory syncytial virus (RSV)-associated acute lower respiratory tract infection (ALRTI) among hospitalized children in the Baoding region of Hebei Province, China. Methods: The study subjects were inpatients diagnosed with ALRTI at a pediatric hospital in Baoding between 1 June 2017 and 31 December 2024. A retrospective analysis was conducted on the detection of RSV and other common respiratory viruses in respiratory specimens to evaluate the clinical epidemiological characteristics of RSV. Viral detection was performed using immunofluorescence (IF) or polymerase chain reaction (PCR) assays. Results: The overall RSV detection rate was 16. 8% (4945/29,399), with 6. 7% co-infections. The RSV detection rate was 29. 8% (2604/8729) in infants younger than 1 year and 18% (942/5232) in the 1-year-old group, then showing a decreasing trend with increasing age, with the lowest rate of 3. 8% (283/7366) observed in the ≥5 years age group. The RSV detection rate decreased from 19. 9% before the COVID-19 pandemic (2017-2019) to around 13% during and after the pandemic (χ = 233. 732, p
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| Concepts | Keywords |
|---|---|
| China | children |
| December | epidemiology |
| Inpatients | infants |
| June | respiratory syncytial virus |
| Virus | seasonality |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | co-infections |
| disease | MESH | COVID-19 pandemic |
| disease | MESH | bch |
| drug | DRUGBANK | Coenzyme M |
| disease | MESH | Respiratory Diseases |
| disease | MESH | RSV infection |
| disease | MESH | infections |
| disease | MESH | respiratory infections |
| drug | DRUGBANK | Flunarizine |
| disease | MESH | included |
| disease | MESH | tracheitis |
| disease | MESH | bronchitis |
| disease | MESH | bronchiolitis |
| disease | MESH | pneumonia |
| disease | MESH | parainfluenza |
| disease | MESH | influenza |