Longitudinal serological detection of exposure to SARS-CoV-2 in a cohort of pregnant women in Malawi: a secondary analysis from a randomised controlled trial.

Publication date: Jun 29, 2026

To investigate whether IgG to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antigens could reveal undetected SARS-CoV-2 exposure in a cohort of Malawian pregnant women participating in the REVAMP clinical trial. A secondary analysis of serological samples from a randomised controlled trial of iron supplementation in pregnancy, which began recruiting women in November 2018 and had its last visit occurring in September 2021. Resource-limited setting in Zomba and Blantyre, Southern Malawi. Pregnant women with ultrasound-confirmed singleton pregnancies in the second trimester, with haemoglobin

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Concepts Keywords
Iron Adult
Malawian Antibodies, Viral
Pregnancy Antibodies, Viral
Randomised COVID-19
COVID-19
COVID-19 Serological Testing
Female
Humans
Immunoglobulin G
Immunoglobulin G
INFECTIOUS DISEASES
Longitudinal Studies
Malawi
Pregnancy
Pregnancy
Pregnancy Complications, Infectious
Public health
SARS-CoV-2
Young Adult

Semantics

Type Source Name
disease MESH severe acute respiratory syndrome
drug DRUGBANK Iron
disease MESH COVID-19
disease MESH INFECTIOUS DISEASES
disease MESH Pregnancy Complications Infectious

Original Article

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