World Health Organization bacterial priority pathogens in skin and soft tissue infections: prevalence, antimicrobial resistance, and risk factors in Mwanza, Tanzania.

Publication date: Sep 01, 2026

Antimicrobial resistance, particularly among World Health Organization bacterial priority pathogens (WHO BPPs), poses a major global health threat. We assessed the epidemiology of wound infections, including bacterial profiles, WHO BPP burden, and associated factors, during and after the implementation of the National Action Plan on Antimicrobial Resistance (NAP-AMR) in Mwanza, Tanzania. A cross-sectional study was conducted during (June 2019 to June 2020) and after (March to August 2023) NAP-AMR. Pus samples were cultured aerobically. Isolates were identified using Vitek mass spectrometry and 16S ribosomal ribonucleic acid sequencing. Antimicrobial susceptibility testing and minimum inhibitory concentrations were determined using Vitek 2. Among 630 patients (median age 29 years; interquartile range 15-47), 257 (40. 8%) had positive cultures. Skin and soft tissue infections increased significantly after NAP-AMR (27. 8% vs 68. 3%, P

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Concepts Keywords
Acinetobacter Gram-negative bacteria
Cultured Gram-positive bacteria
Mwanza
Spectrometry

Semantics

Type Source Name
disease MESH soft tissue infections
disease MESH wound infections
disease MESH BPP
disease MESH Plan
disease MESH Pus
drug DRUGBANK Meropenem
disease MESH coronavirus disease 2019

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