Analysis of factors influencing SARS-CoV-2 infection and outcomes in patients with chronic lymphocytic leukemia during the burst of COVID-19 epidemic.

Publication date: Jul 01, 2026

CLL patients have immune deficiencies and are at high risk of SARS-CoV-2 infection. Limited research exists on risk factors and survival outcomes of SARS-CoV-2 infection in Asian CLL patients during the COVID-19 pandemic. Therefore, this study aims to explore the relationship between SARS-CoV-2 infection and survival in this population. A retrospective analysis was conducted on 119 CLL patients treated at a large tertiary comprehensive hospital in western China from January 2020 to May 2023, coinciding with a surge in the epidemic in the city. (1) During the epidemic, the treatment group had a higher proportion of males, second-line and initial treatment, 11q- chromosome, LDH level, and lower erythrocyte count (P 

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Concepts Keywords
China Chronic lymphocytic leukemia
Hospital COVID-19
Leukemia Infection
Retrospective Survival outcome
Treatment

Semantics

Type Source Name
disease MESH Infection
drug DRUGBANK Coenzyme M
drug DRUGBANK Aspartame
disease MESH included
pathway REACTOME Reproduction
disease MESH chronic lymphocytic leukemia
pathway REACTOME SARS-CoV-2 Infection
disease MESH SARS-CoV-2 infection

Original Article

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