Life Course Vaccination Continuum (LCVAC): An Expert Consensus on Life Course Vaccination in India.

Publication date: May 01, 2026

India’s immunization program focuses predominantly on children, leaving adults vulnerable to vaccine-preventable diseases (VPDs). The COVID-19 pandemic further disrupted routine vaccination. A life course approach (LCA) is needed to address these gaps. However, implementation of adult vaccination programs in low- and middle-income countries (LMICs) remains challenged by inequities in healthcare access, infrastructural limitations, and variable awareness regarding adult immunization. A 16-member expert panel from pulmonology, geriatrics, oncology, obstetrics, nephrology, diabetology, and life sciences reviewed literature (2014-2023) from MEDLINE, Scopus, and Cochrane databases. Using a structured, evidence-based grading approach, the panel formulated consensus recommendations for adult vaccination in India. The Life Course Vaccination Continuum (LCVAC) proposes three target groups: adults aged 18-59 years with comorbidities; elderly ≥60 years with or without comorbidities; and healthy adults aged 18-60 years. Key recommended vaccines include Tdap (every 10 years), influenza (annual), pneumococcal (PCV13/PPSV23 series), zoster (for ≥50 years), hepatitis B, meningococcal, and hepatitis A (risk-based). Major barriers identified include vaccine hesitancy, cost, access limitations, and inadequate provider prioritization. Life Course Vaccination Continuum provides the first comprehensive expert consensus on life course vaccination in India. The framework is intended to complement broader public health strengthening efforts, and its successful implementation will require vaccine awareness campaigns, healthcare professional education, equitable access strategies, and the establishment of dedicated adult vaccination centers nationwide.

Open Access PDF

Concepts Keywords
Oncology immunisation policy
Pandemic indian vaccination programs
Vaccination life course vaccination
preventive health strategies
public health
vaccine accessibility

Semantics

Type Source Name
disease MESH vaccine-preventable diseases
disease MESH COVID-19 pandemic
disease MESH LCA
disease MESH influenza
disease MESH zoster
disease MESH hepatitis B
pathway KEGG Hepatitis B
disease MESH hepatitis A
pathway REACTOME Reproduction
disease MESH Infectious Disease
pathway REACTOME Infectious disease
drug DRUGBANK Coenzyme M
disease MESH hepatitis
drug DRUGBANK Alpha-1-proteinase inhibitor
disease MESH included
disease MESH pneumonia
disease MESH Measles
pathway KEGG Measles
disease MESH mumps
disease MESH rubella
drug DRUGBANK Isoxaflutole
disease MESH ICS
disease MESH pneumococcal infection
disease MESH meningococcal disease
disease MESH Tetanus
disease MESH Diphtheria
disease MESH Pertussis
pathway KEGG Pertussis
disease MESH bacterial infections
disease MESH chronic illnesses
disease MESH strains
pathway KEGG Virion
disease MESH asthma
pathway KEGG Asthma
disease MESH malnutrition
drug DRUGBANK Medical air
disease MESH bacterial pneumonia
disease MESH infections
disease MESH heart disease
drug DRUGBANK Penciclovir
disease MESH postherpetic neuralgia
disease MESH PHN
disease MESH herpes zoster ophthalmicus
disease MESH dementia
disease MESH varicella
disease MESH HIV infection
pathway REACTOME HIV Infection
disease MESH hematologic malignancies
disease MESH liver cancer
disease MESH liver disease
drug DRUGBANK Dimethyl sulfone
disease MESH meningitis
disease MESH bacterial meningitis
disease MESH complement deficiencies
pathway REACTOME Immune System
disease MESH pain
disease MESH fever
disease MESH Japanese encephalitis
disease MESH rabies
disease MESH yellow fever
drug DRUGBANK Varicella Zoster Vaccine (Live/Attenuated)
drug DRUGBANK Aspartame
drug DRUGBANK Etoperidone
drug DRUGBANK Clostridium tetani toxoid antigen (formaldehyde inactivated)
disease MESH Dis
disease MESH hcp
disease MESH Rai
disease MESH herpes simplex
disease MESH syphilis
disease MESH virus infection
disease MESH typhoid
drug DRUGBANK Hepatitis B Vaccine (Recombinant)
drug DRUGBANK Vorinostat
disease MESH emergency
drug DRUGBANK Spinosad

Original Article

(Visited 8 times, 1 visits today)

Leave a Comment

Your email address will not be published. Required fields are marked *