Publication date: Jul 23, 2026
Suicidal ideation (SI) is a major global concern, yet its dynamic interplay with other symptoms remains poorly understood. To identify symptoms that co-fluctuate with or temporally precede SI to better understand symptom dynamics. Longitudinal data from three Dutch psychiatric cohorts with lifetime internalising disorders (16 waves from April 2020 until February 2022) were collected during the COVID-19 pandemic. We analysed depressive, happiness, anxiety, loneliness, worry symptoms and COVID-19-specific items only in those participants with SI fluctuations. Dynamic time warping (DTW) quantified within-person similarity between symptom trajectories and SI and results were aggregated at the group level. 307 participants (mean age 44. 8 years; 61. 6% female) showed increasing SI over time (p

Semantics
| Type | Source | Name |
|---|---|---|
| drug | DRUGBANK | Tropicamide |
| disease | MESH | COVID-19 pandemic |
| disease | MESH | anxiety |
| disease | MESH | Depressive Disorder |