Magnesium deficiency and long-term incident dementia among COVID-19 survivors: a propensity score-matched cohort study.

ingentiumby ingentium

In Clinical Literature.

Publication date: May 03, 2026

COVID-19 survivors face an elevated risk of long-term cognitive decline, yet potentially modifiable factors that shape post-COVID dementia trajectories remain insufficiently characterized. Low magnesium status has been linked to dementia risk in general populations, but whether low magnesium status is associated with long-term dementia risk among COVID-19 survivors remains unclear. This propensity score-matched retrospective cohort study used the TriNetX Global Collaborative Network to examine the association between low serum magnesium (

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Concepts Keywords
COVID-19
dementia
magnesium deficiency
mild cognitive impairment
neurodegeneration
propensity score matching

Semantics

Type Source Name
disease MESH Magnesium deficiency
disease MESH dementia
disease MESH COVID-19
disease MESH face
disease MESH cognitive decline
drug DRUGBANK Magnesium
disease MESH included
disease MESH Alzheimer’s disease
disease MESH vascular dementia
drug DRUGBANK Coenzyme M
pathway REACTOME Reproduction
disease MESH infection
disease MESH neuroinflammation
disease MESH injury
disease MESH stroke
disease MESH ICD
disease MESH neurodegenerative disorders
disease MESH bipolar disorder
disease MESH schizophrenia
disease MESH psychotic disorders
disease MESH cerebral infarction
disease MESH intracerebral hemorrhage
disease MESH vascular diseases
disease MESH inflammation
pathway REACTOME Glucose metabolism
drug DRUGBANK Isoxaflutole
disease MESH SMDs
disease MESH SMD
disease MESH death
disease MESH Hypocalcemia
drug DRUGBANK Calcium
disease MESH appendicitis
disease MESH reinfection
disease MESH primary hypertension
disease MESH Neoplasms
disease MESH Diabetes mellitus
disease MESH Ischemic heart diseases
disease MESH Overweight
disease MESH obesity
disease MESH Anxiety
disease MESH mental disorders
disease MESH Sleep disorders
disease MESH affective disorders
disease MESH Nicotine dependence
disease MESH Heart failure
disease MESH Atrial fibrillation
disease MESH Vitamin deficiency
disease MESH Alcohol related disorders
disease MESH Cerebrovascular diseases
disease MESH Malnutrition
drug DRUGBANK Cyanocobalamin
drug DRUGBANK Benzodiazepine
disease MESH chronic kidney disease
disease MESH HRs
drug DRUGBANK Methionine
disease MESH hypertension
pathway REACTOME Neurodegenerative Diseases
disease MESH critical illness
disease MESH hypoxia
disease MESH liver disease
disease MESH anemia
disease MESH frailty
disease MESH long COVID
disease MESH Park
disease MESH Dis
disease MESH CAM
disease MESH brain injury
disease MESH neurological disorders
disease MESH migraine
disease MESH mixed dementia
disease MESH Muh
drug DRUGBANK Sugammadex
drug DRUGBANK Neostigmine
disease MESH atelectasis
drug DRUGBANK Diethylstilbestrol
disease MESH Des
drug DRUGBANK Magnesium oxide
disease MESH severe acute respiratory syndrome
disease MESH coronavirus infection

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