Publication date: Jul 30, 2026
Recently, deep learning has emerged as a prominent branch of AI, gaining attention for its high accuracy and wide-ranging application in various domains. The proposed Explain-COVIDNet framework enhances COVID-19 detection from chest X-ray images by addressing key limitations in current deep learning models, including poor interpretability, sensitivity to noise, and limited clinical reliability. It begins with a robust preprocessing stage using a Wavelet Contrast Enhancer (WCE), which integrates Discrete Wavelet Transform (DWT) for denoising and Contrast-Limited Adaptive Histogram Equalization (CLAHE) for contrast enhancement. This results in high-quality input images that aid model accuracy. Medical GoogLeNet, a 154-layer architecture with inception modules, is used for deep feature extraction and classification, employing Leaky ReLU to retain subtle but crucial image details. To improve transparency, XGrad-CAM is incorporated for explainability, generating class-specific heatmaps that highlight diagnostically relevant lung regions. The model demonstrates strong performance on two benchmark datasets, achieving up to 95. 73% accuracy, 95. 72% F1-score, 99. 39 AUC, and 91. 22 Cohen’s Kappa, while maintaining computational efficiency. These results underscore Explain-COVIDNet’s potential as a reliable, interpretable, and clinically meaningful tool for automated COVID-19 diagnosis.

| Concepts | Keywords |
|---|---|
| F1 | Chest X-ray |
| Googlenet | CLAHE |
| Reliable | COVID-19 detection |
| Stage | Discrete Wavelet Transform |
| Ultrasound | Explainable AI |
| Medical GoogLeNet | |
| Wavelet Contrast Enhancer | |
| XGrad-CAM |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | COVID-19 |
| disease | MESH | image |
| disease | MESH | CAM |