SCAGC-UNet: Graph Convolutional Network with Spatial and Channel Attention for Medical Image Segmentation.

Publication date: Jul 06, 2026

Medical image segmentation is critical for clinical diagnosis, yet existing methods face a persistent trade-off: CNN-based approaches are constrained by local receptive fields, while Transformer-based methods suffer from semantic dilution when modeling global context. To address these limitations, we propose SCAGC-UNet, a region-aware graph convolutional network that bridges local detail extraction and global dependency modeling through structured region-level reasoning. The architecture features a dual-layer residual encoder for hierarchical feature extraction and a Spatial-Channel Graph Convolution (SC-GCN) module at the bottleneck, which simultaneously captures inter-region spatial topology and intra-region channel semantics via dual-branch graph inference. Feature refinement in the decoder is further enhanced by Context-Corrected Modules and Backward-Aided Modules to reduce the semantic gap across skip connections. We validate SCAGC-UNet on three public benchmarks covering distinct imaging challenges. On Kvasir-SEG, the model achieves a Dice score of 92. 28% and MIOU of 92. 41%, surpassing the strongest CNN-based baseline CCBANet by 0. 73% in DSC and outperforming TransUNet by 11. 76% in DSC. On BUSI, it attains an IOU of 78. 10% and MIOU of 87. 68%, outperforming UNet by 2. 82% in IOU and TransUNet by 6. 91% in DSC. On COVID-19 CT, it achieves a DSC of 82. 51%, surpassing UNet by 4. 99% and TransUNet by 7. 47%, demonstrating robust performance on irregular lesion morphologies. These results confirm that SCAGC-UNet achieves consistent and robust segmentation performance across three public benchmark datasets spanning distinct imaging modalities, suggesting its potential clinical relevance.

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Concepts Keywords
Bottleneck graph convolutional networks
Cnn medical image segmentation
Ct spatial-channel attention
Informatics

Semantics

Type Source Name
disease MESH Image
disease MESH face
disease MESH COVID-19
drug DRUGBANK Coenzyme M
disease MESH plan
drug DRUGBANK Spinosad
drug DRUGBANK Flunarizine
disease MESH tumor
drug DRUGBANK Trinitrotoluene
disease MESH OS2
disease MESH CCMs
disease MESH BAMs
disease MESH CCM
disease MESH gra
disease MESH included
disease MESH RCC
disease MESH colonic polyp
drug DRUGBANK Resiniferatoxin
disease MESH Acc
drug DRUGBANK Methionine
disease MESH polyp
drug DRUGBANK Isoxaflutole
disease MESH ers
disease MESH RDC
drug DRUGBANK Trestolone
pathway REACTOME Translation
drug DRUGBANK Sulpiride
disease MESH Lymph Node Metastasis
drug DRUGBANK Guanosine
drug DRUGBANK (S)-Des-Me-Ampa
disease MESH Brain Tumor
disease MESH injury

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