Publication date: Aug 14, 2026
Although numerous studies have investigated the association between hypertension and coronavirus disease 2019 (COVID-19) severity, differences in study characteristics have limited the consistency and generalizability of the available evidence. This systematic review and meta-analysis systematically evaluated the association between hypertension and COVID-19 severity by synthesizing evidence from 30 studies involving 15,549 participants comparing the prevalence of hypertension in non-severe and severe COVID-19 patients. Pooled odds ratios (ORs) were calculated using a random-effects model. Heterogeneity was assessed using I^2 and τ^2 statistics, while subgroup analyses and meta-regression examined the effects of region, sample size, study quality, age, and gender. Publication bias was evaluated using funnel plots and Egger’s test. Hypertension was more frequently observed in severe COVID-19 cases across the included studies with a pooled odds ratio (OR) of 2. 73 (95% CI: 1. 85-4. 02, p
| Concepts | Keywords |
|---|---|
| Analysis | |
| Covid | |
| Evaluated | |
| Evidence | |
| Hypertension | |
| Investigated | |
| Meta | |
| Non | |
| Numerous | |
| Odds | |
| Pooled | |
| Prevalence | |
| Severe | |
| Severity | |
| Systematic |
Semantics
| Type | Source | Name |
|---|---|---|
| disease | MESH | hypertension |
| disease | MESH | COVID-19 |
| disease | MESH | included |
| disease | MESH | Long Covid |